European Registry of Next Generation Imaging in Advanced Prostate Cancer
Recruiting · NCT06866782 · Observational (researchers observe without assigning treatment) · Lead sponsor: Fundacio Puigvert
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The RING study is a European registry collecting real-world data on advanced prostate cancer (APC) imaging. It aims to evaluate the role of next-generation imaging (NGI), such as PET/CT and whole-body MRI, in detecting and monitoring the disease compared to conventional imaging. Men aged 18 or older with histologically confirmed prostate cancer are eligible to participate in the study if they require imaging to assess potential metastases, either at diagnosis or after relapse and sign a consent form. Patients will receive standard care with no experimental treatments. Imaging and treatment decisions will follow routine clinical practice. Data will be collected from medical records and analysed for research. This study will help doctors understand when NGI should be used, how it affects treatment decisions, and its impact on patient outcomes.
Who can take part
Inclusion criteria
- Adult male patients (≥18 years with no upper age limit).
- Histologically proven prostate cancer.
- Patients who require imaging exploration (conventional, Next-Generation Imaging (NGI), or their combination) at high risk for harbouring metastatic deposits at the hormone-sensitive stage, either at the diagnostic workout of a "naïve" patient or at biochemical relapse/progression after local treatment.
- Patients who authorize their participation in the study by signing a written informed consent form (ICF).
Exclusion criteria
- Patients participating in other interventional or non-interventional study which requires NGI as a triage test for metastatic assessment.
- Patients with evidence of any other clinically significant disease or condition which in the opinion of the investigator discourages their participation in the study.
- Patients who will not be able to complete the study.
Where it is running
24 locations listed.
- Fundació Puigvert - Barcelona, Spain
- Hospital de la Santa Creu i Sant Pau - Barcelona, Spain
- IRCCS Universit of Bologna - Bologna, Italy
- Bonn University Hospital - Bonn, Germany
- Hospital Universitario Reina Sofia - Córdoba, Spain
- Azienda Ospedaliero-Universitaria Careggi - Florence, Italy
- Azienda Ospedaliero-Universitaria Careggi - Florence, Italy
- Martini Klinik - Hamburg, Germany
- Uniwersytet Jagielloński Collegium Medicum - Krakow, Poland
- Universitair Ziekenhuis Leuven - Leuven, Belgium
- Hospital Center University De Lille - Lille, France
- Hospices Civils de Lyon - Lyon, France
- Hospital Universitario La Paz - Madrid, Spain
- Hospital Universitario Ramón y Cajal - Madrid, Spain
- Skånes universitetssjukhus Malmö - Malmö, Sweden
- IRCCS Ospedale San Raffaele - Milan, Italy
- München LMU L MU-University Clinic - Munich, Germany
- University Hospitals Pitié Salpêtrière - Paris, France
- Urologische Klinik München - Planegg - Planegg, Germany
- ERASMUS MC & Franciscus Hospital - Rotterdam, Netherlands
- Hospital Universitario de Canarias - San Cristóbal de La Laguna, Spain
- Hospital Universitario Marqués de Valdecilla - Santander, Spain
- Hospital Clínico Universitario de Santiago - Santiago de Compostela, Spain
- Universitätsklinik Tübingen - Tübingen, Germany