Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's Disease
Recruiting · NCT06874803 · Interventional (participants receive a specific treatment) · Lead sponsor: Jiani Wu
View the official record on ClinicalTrials.gov →Interventions studied
Acupuncture and Moxibustion (AM)Sham Acupuncture and Moxibustion (Sham-AM)
What this trial is about
This study evaluates the clinical effect and safety of acupuncture combined with moxibustion in improving motor symptoms of early-stage Parkinson's Disease (PD) patients, by assessing the changes in UPDRS scores. It also explores objective factors affecting the acupuncture effect and investigates the functional MRI mechanisms of acupuncture in PD treatment.
Who can take part
Age range
30 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Participants must meet all of the following criteria:
- \. Diagnosed with Parkinson's disease (PD) according to the 2016 Chinese 2. Diagnostic Criteria for Parkinson's Disease.
- \. Hoehn-Yahr stage \<3 (mild to moderate PD). 4. Age between 30 and 80 years (inclusive). 5. Signed informed consent indicating voluntary participation.
Exclusion criteria
- Participants meeting any of the following criteria will be excluded:
- Diagnosed with Parkinson-plus syndromes or other secondary parkinsonism.
- Prior history of deep brain stimulation (DBS) surgery.
- Severe cerebrovascular disease, brain trauma, or history of craniotomy.
- Severe dementia or psychiatric disorders that prevent cooperation with study procedures.
- Severe coagulation disorders.
- Presence of severe systemic organ dysfunction (cardiac, pulmonary, hepatic, renal, endocrine, or metabolic disorders).
- Pregnant or breastfeeding women.
- History of allergic reaction to acupuncture or moxibustion.
- Prior treatment with acupuncture or moxibustion within the past three months.
- Participation in another clinical trial within the past three months.
Where it is running
1 location listed.
- Guang'anmen Hospita, China Academy of Chinese Medical Sciences - Beijing, Beijing Municipality, China