Detection of Internal Tremors by Oscillometry in Parkinson's Patient
Recruiting · NCT06885541 · Interventional (participants receive a specific treatment) · Lead sponsor: University Hospital, Toulouse
View the official record on ClinicalTrials.gov →Interventions studied
Detection of objective internal tremors
What this trial is about
The goal of the present study is to objectively access the presence of an Internal Tremor in Parkinson's disease. Inertial sensors will be used to detect the presence of a rhythmic oscillation of 3-4 Hz. The study will be performed in both Parkinson's disease patients and healthy controls to ascertain the specificity of this type of tremor.
Who can take part
Age range
18 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- For the experimental group)
- Patient with idiopathic parkinson's disease
- Mini Mental State Evaluation score above or equal to 25
- Hoehn and Yahr scale score of ≤3 in the OFF phase, with postural stability allowing the patient to stand unaided for 1 minute.
- Able to walk unassisted
- Willing to undergo accelerometry in the OFF state
- For the control group)
- Healthy volunteer subjects matched for age (+/- 5 years) and sex
- Mini Mental State Evaluation score above or equal to 25
Exclusion criteria
- For the experimental group)
- Patients with an atypical parkinsonian syndrome
- Patients unable to walk or stand for more than one minute in the off state
- Parkinson's patients treated with deep brain stimulation, apomorphine pump, or duodopa intestinal infusion, and foslevodopa
- Pregnant patients
- Major osteoarticular problems
- Neurological condition that may affect gait
- For the control group)
- Participants with significant gait impairment (osteoarticular disorder)
- Those with a neurological disease that, in the investigator's judgment, may interfere with the study's outcome measure
- Participants with a clinical tremor that may interfere with the measurement of the primary outcome (e.g., essential tremor, thyroid disease, or tremors induced by medication)
- Pregnant participants
Where it is running
1 location listed.
- Purpan Hospital - Toulouse, Occitanie, France