Circadian Rhythms in Human Adipose
Recruiting · NCT06891534 · Interventional (participants receive a specific treatment) · Lead sponsor: Mayo Clinic
View the official record on ClinicalTrials.gov →Interventions studied
Continuous FeedingIntermittent feeding
What this trial is about
The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.
Who can take part
Age range
18 Years to 55 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- BMI 20-25 kg/m2 or 30-37 kg/m2
- For participants with obesity a waist-to-hip ratio of ≥0.95 in males and ≥0.90 in females.
- sedentary
- females: non pregnant or breastfeeding
- ability to provide written informed consent and follow study instructions
Exclusion criteria
- History of mediations that impact adipocyte/lipid metabolism
- smoking
- insomnia
- sleep apnea
- sleep medication use
- employment in night or shift work
- extreme chronotypes
- Allergy to lidocaine
Where it is running
1 location listed across 1 US state.
- Mayo Clinic - Rochester, Minnesota, United States