Comparison of Different Methods of CAPTure of Circulating Tumour Cells (CTC) in Patients With Metastatic Breast or Prostate Cancer

Recruiting · NCT06904625 · Interventional (participants receive a specific treatment) · Lead sponsor: Institut Claudius Regaud

View the official record on ClinicalTrials.gov →

Breast cancer Prostate cancer

Interventions studied

Taking blood samples before starting treatment

What this trial is about

This trial is a pilot, prospective, single-center study conducted in a population of patients with metastatic breast cancer (whatever the immunohistochemical subtype) or metastatic prostate cancer. The aim of this exploratory study is to compare the sensitivity of three different techniques (CellSearch®, Parsortix® and SmartCatch®) in detecting circulating tumor cells (CTCs). After the patient's agreement, and before starting anti-tumor treatment, a blood sample will be taken using the 3 different CTC detection techniques. Each patient will participate in the study for one day. A total of 54 evaluable patients (36 patients with metastatic breast cancer and 18 patients with metastatic prostate cancer) will be included in this interventional study.

Who can take part

Age range

18 Years and older

Sex

All (male and female)

Healthy volunteers

No - a diagnosis or condition is required

Phase

Not applicable (e.g. observational or device study)

Study type

Interventional (participants receive a specific treatment)

Inclusion criteria

Patient with breast cancer (whatever the immunohistochemical subtype: triple-negative, RH+/HER2-negative or HER2-positive) or prostate cancer, multi-metastatic, eligible for a new line of treatment.
Patient not yet initiated on a new specific treatment for breast or prostate cancer at inclusion.
Age ≥ 18 years and WHO ≤ 2
Patient affiliated to Social Security scheme in France.
Patient having signed informed consent prior to inclusion in the study and prior to any study-specific procedures.

Exclusion criteria

Associated pathology(ies) likely to prevent the study procedure from running smoothly
Any psychological, family, geographical or sociological condition that prevents compliance with the medical follow-up and/or procedures stipulated in the study protocol.
Patient deprived of liberty or under legal protection (guardianship, legal protection)
Patient who has had another solid tumor (excluding carcinoma in situ of the breast or cervix) within 5 years.

Where it is running

2 locations listed.

IUCT-O - Toulouse, France
IUCT-O - Toulouse, France

Read the full protocol, contacts and eligibility on ClinicalTrials.gov →