Study of the Impact of Time of Vaccination on Response to Influenza Vaccine in Patients With Chronic Renal Failure

Recruiting · NCT06907667 · Interventional (participants receive a specific treatment) · Lead sponsor: Centre Hospitalier Universitaire de Nice

Interventions studied

Vaccine injection

Immune response to influenza vaccine in patients with chronic renal insufficiency.

Age range

18 Years to 100 Years

Sex

All (male and female)

Healthy volunteers

No - a diagnosis or condition is required

Phase

Not applicable (e.g. observational or device study)

Study type

Interventional (participants receive a specific treatment)

Chronic renal failure patient at stage 4 or 5 (i.e. estimated GFR \< 30mL/min/1.73m2); or Dialysis patient; or renal transplant patient regardless of GFR;
Age ≥ 18 years;
Indication for influenza vaccination;
Express free and informed consent.

Known hypersensitivity to influenza vaccine or egg proteins;
Previous influenza vaccination for the current season;
Current infection;
Current acute illness;
Treatments with a major impact on vaccine response:
Treatment of rejection within the previous 3 months;
Renal transplantation with induction performed within the previous 6 months;
Immunosuppressive treatment including CTLA4 agonist, complement inhibitor, anti-CD20;
Treatments that may distort the serological response: Polyvalent immunoglobulin infusion within the preceding 3 months;
Vulnerable persons (minors, adults under guardianship or trusteeship, persons deprived of their liberty, persons unable to speak French);
Subjects not affiliated to Social Security.

1 location listed.