Infectious Complications After Esophagectomy
Recruiting · NCT06911658 · Observational (researchers observe without assigning treatment) · Lead sponsor: Assistance Publique - Hôpitaux de Paris
View the official record on ClinicalTrials.gov →What this trial is about
Infectious complications represent the most common postoperative adverse events following esophagectomy for cancer, such as pneumonia (15% of cases). These complications increase immediate risks, lengthen hospital stays, and worsen patient quality of life. The population includes patients admitted to intensive care after esophagectomy for cancer between January 1, 2017, and December 31, 2024. The study focuses on this population due to the increasing incidence of esophageal cancer, the increased use of surgery for these indications, and the importance of postoperative infections in these complex procedures, despite their understudied nature in the current literature. Identifying modifiable risk factors could lead to corrective measures and thus improve the prognosis of postoperative patients. The research focuses primarily on the incidence, types, factors, and prognosis associated with the occurrence of infections after esophagectomy for cancer. It also includes an analysis of the pathogens involved, their resistance profiles, and the antibiotic therapies used in first-line probabilistic treatment.
Who can take part
Inclusion criteria
- Patients over 18 years of age
- Underwent esophagectomy for cancer between January 1, 2017, and December 31, 2024
- Scheduled admission to intensive care for postoperative monitoring
Exclusion criteria
- Opposition to the use of data
Where it is running
2 locations listed.
- Hôpital Saint-Louis - APHP - Paris, France
- Saint Louis Hospital - Paris, France