Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis
Recruiting · NCT06919900 · Interventional (participants receive a specific treatment) · Lead sponsor: Georgia State University
View the official record on ClinicalTrials.gov →Interventions studied
Perturbation TrainingTreadmill Walking
What this trial is about
The primary purpose of this interventional study is to examine the overall motor learning capacity from exposure to repeated perturbations among ambulatory people with multiple sclerosis (MS). This project will advance our understanding of learning new motor skills from exposure to external perturbations. If it is proven that people with MS can learn motor skills from perturbation training, the findings from this study will pave a theoretical foundation for applying perturbation training as a promising fall prevention intervention for people with MS.
Who can take part
Age range
45 Years to 89 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Clinically confirmed multiple sclerosis
- At least 45 years old
- Able to walk independently at least 25 feet
- Able to stand independently for at least 30 seconds
- Patient Determined Disability Steps score between 0 and 4
- Free from pregnancy
- Montreal Cognitive Assessment score of 23 or higher
Exclusion criteria
- Previous experience with perturbation training
- T-score from the dual x-ray absorptiometry (DXA) scan of less than -2.5
- Coexisting psychiatric disorders or other neurological conditions, severe medical illness, or cardiovascular diseases
- Participants have had a relapse in the past 8 weeks
Where it is running
1 location listed across 1 US state.
- Georgia State University Biomechanics Lab - Atlanta, Georgia, United States