Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine
Recruiting · NCT06951802 · Interventional (participants receive a specific treatment) · Lead sponsor: Insel Gruppe AG, University Hospital Bern
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
RCT comparing intraoperative administration of low-dose ketamine during laparoscopic endometriosis operation and the postoperative pain outcome
Who can take part
Age range
18 Years and older
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Patients undergoing surgery for endometriosis operation requiring general anaesthesia at the Inselspital, Bern University Hospital, University of Bern, Department of gynaecology and obstetrics.
- Age ≥ 18 years
- American Society of Anesthesiologist (ASA) physical status 1-3
- Patients with known or suspected endometriosis
- Written informed consent.
Exclusion criteria
- Age \< 18 years
- ASA physical status ≥4
- Higher-grade atrioventricular block without pacemaker
- Severe hypovolemia or bradycardia
- Uncontrolled hyper- or hypotension
- Liver disease
- Known malignant hyperthermia
- Cardiovascular instability or severe heart failure (New York Heart Association classification (NYHA) \> III)
- Myocardial infarction during the last 30 days prior to surgery
- Increased intracranial or increased intraocular pressure
- Limited peripheral autonomic activity, hypersensitivity to ketamine or propofol or its components
- Pregnancy
- Rejection or lack of consent of the patient or relatives
Where it is running
1 location listed.
- Inselspital Bern - Bern, Switzerland