Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study
Recruiting · NCT06965335 · Observational (researchers observe without assigning treatment) · Lead sponsor: Niguarda Hospital
View the official record on ClinicalTrials.gov →Interventions studied
BIOLOGICAL STUDY aiming at describing clinicophatological features of EO-CRC vs SO-CRC
What this trial is about
Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibactin as well as a broader proteo-genomic characterization, to identify potential new therapeutic targets specifically directed to this peculiar subset of patients.
Who can take part
Age range
18 Years to 40 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Eligibility criteria (as published)
1. Patients with diagnosis of colorectal cancer (vEO-CRC: 18-40 years of age), or SO-CRC diagnosed later than age 60;
2. Informed consent signature from alivepatient;
3. Availability of formalin-fixed paraffin embedded (FFPE) tumor samples (5 FFPE 4uM thick slides and 10 FFPE 10 uM thick slides) and/or fresh tumor tissue retrieved from a biopsy or surgical procedure performed as per clinical standard of care.
Where it is running
1 location listed.
- ASST Grande Ospedale Metropolitano Niguarda - Milan, Milano, Italy