HIIT in Sedentary Obese Adults: Effects on Metabolic Risk, Body Composition, and FABP4
Recruiting · NCT06973980 · Interventional (participants receive a specific treatment) · Lead sponsor: Eastern Mediterranean University
View the official record on ClinicalTrials.gov →Interventions studied
Exercise
What this trial is about
It is aimed to investigate the responses of Fatty Acid Binding Protein 4 (FABP4), which has been discovered as a novel biomarker of obesity and metabolic diseases, to regular exercise training. The aim of this study is to investigate the effects of high-intensity interval training (HIIT) on cardiometabolic risk factors, body composition, and plasma FABP4 levels in sedentary obese adults.
Who can take part
Age range
20 Years to 35 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Aged between 20 and 35 years,
- BMI between 30 and 35 kg/m²,
- Waist circumference of 90-100 cm for women, 105-110 cm for men,
- Sedentary lifestyle (\<600 MET-min/week),
- Referred by a physician (with a statement confirming no contraindication to exercise)."
Exclusion criteria
- BMI \> 35,
- Pregnancy,
- Cardiovascular Diseases: Individuals with serious cardiovascular issues, such as uncontrolled hypertension, heart failure, coronary artery disease, or a heart attack within the last 6 months, which could pose a risk during exercise.
- Respiratory Diseases: Individuals with chronic respiratory conditions, such as uncontrolled or severe asthma or COPD, who cannot tolerate exercise due to their condition.
- Neurological Disorders: Individuals with neurological issues that limit exercise capacity, such as Parkinson's disease, stroke, or multiple sclerosis.
- Musculoskeletal Issues: Individuals with chronic musculoskeletal problems, particularly knee or hip osteoarthritis, that may increase the risk of pain or injury during exercise.
- Metabolic or Endocrine Disorders: Individuals with uncontrolled metabolic issues, such as diabetes or thyroid disorders, that could cause blood sugar or hormonal fluctuations during exercise.
- Acute Infections or Illness: Individuals with acute infections, fever, or recently undergone surgical procedures.
- Any health condition that may prevent participation in exercise."
Where it is running
1 location listed.
- Eastern Mediterranean University - Famagusta, Cyprus