A Study of the MIND Diet for Persons With Multiple Sclerosis
Recruiting · NCT06992115 · Interventional (participants receive a specific treatment) · Lead sponsor: Icahn School of Medicine at Mount Sinai
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
This study will assess the impact of a MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet on brain health and MS symptoms. Participants will be randomly assigned to one of two arms: the diet intervention arm or the "continue current diet"/control arm. Participants randomized to the dietary intervention arm will change their diet to follow a MIND dietary pattern for one year; diet-related education and programming is provided to support this change. Participants randomized to the continue/control arm will be asked to continue their current dietary habits, without major change for one year; multiple sclerosis (MS) MS-related related education and programming (unrelated to diet) is provided. All participants will be asked to provide blood \& stool samples and to complete online questionnaires \& three in-person assessments.
Who can take part
Inclusion criteria
- Ages 18-70 years, inclusive
- MS diagnosis, on any treatment (including no treatment)
- MIND diet score of ≤8 at baseline
- NfL parameters determined by age
Exclusion criteria
- Diagnosis of an additional neurodegenerative disease (e.g. Alzheimer's) or other serious neurological condition (e.g. stroke)
- Current serious medical condition that could impact the ability to participate or influence study results (e.g. cancer, HIV)
- Pregnancy/planning during study period
Where it is running
1 location listed across 1 US state.
- Mount Sinai Hospital - New York, New York, United States