Stable Isotopes- Adults With Obesity
Recruiting · NCT07020741 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Illinois at Urbana-Champaign
View the official record on ClinicalTrials.gov →Interventions studied
Indispensable Amino Acid OxidationStable Isotope Oral Glucose Tolerance Test
What this trial is about
In a crossover design, 8 participants will receive caloric drinks containing stable isotopes. In one arm of the study, participants will consume 6 hourly drinks containing two stable isotopes. Repeated blood, breath, urine, and muscle biopsies will be taken. In the second arm, participants will consume 1 drink containing 75g glucose, labeled with two stable isotopes of glucose. Periodic blood and breath will be taken over three hours.
Who can take part
Age range
19 Years to 59 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- ages 19-59
- Obese \>/= 30 kg/m\^2 and \>/= 102 cm for males and \>/= 88 cm for females
- Godin Leisure-time or exercise questionnaire \<14 units
Exclusion criteria
- Pregnant or become pregnant
- Any known food allergies
- Smoker
- Are physically active
- Have any known metabolic diseases
- Have been weight unstable within the last 6 months (lost or gained \>10% of body mass)
- Non eumenorrheic or on a hormonal birth control
Where it is running
1 location listed across 1 US state.
- Freer Hall - University of Illinois - Urbana, Illinois, United States