Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.
Recruiting · NCT07034599 · Interventional (participants receive a specific treatment) · Lead sponsor: Karlsburg Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Negative pressure ventilationpositive pressure ventilation
What this trial is about
All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- All patients after implantation of a durable left ventricular assist device
Exclusion criteria
- Complication during surgery like bleeding, emergency, inability to fit the cuirass, unavailability of an investigator, unstable condition regarding circulation or ventilation
Where it is running
1 location listed.
- Klinikum Karlsburg - Karlsburg, Germany