NICardipine for Fast Achievement of Systolic BP Targets in ICH
Recruiting · NCT07044232 · Interventional (participants receive a specific treatment) · Lead sponsor: Aarhus University Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Glyceryl trinitrateNicardipine
What this trial is about
Quality improvement study with a quasi-randomized design. The study monitors the effect of a gradually implemented treatment algorithm prioritizing intravenous antihypertensives (e.g., nicardipine) over long-acting nitrate patches. It aims to increase the proportion of patients reaching target systolic BP \<140 mmHg within 1 hour of hospital admission while monitoring safety, clinical outcomes, and healthcare resource utilization.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age ≥18 years
- Acute spontaneous Intracerberal Hemorrhage confirmed by imaging
- Symptom onset to stroke center admission \<6 hours
- Elevated systolic blood pressure (\>140 mmHg) at admission
Exclusion criteria
- Secondary causes of ICH (e.g., trauma, vascular malformation)
- Presumed fatal bleeding at admission
- Short remaining life expectancy (\<12 month)
Where it is running
1 location listed.
- Aarhus University Hospital - Aarhus, Denmark