Multi-omics Detection Techniques for Differentiating Benign and Malignant Pulmonary Nodules
Recruiting · NCT07047573 · Observational (researchers observe without assigning treatment)
View the official record on ClinicalTrials.gov →Interventions studied
PBMCS were isolated from the peripheral blood of hospitalized patients with pulmonary nodules and incubated with nanoparticles loaded with tumor antigens for a specific period of time to detect cancer
What this trial is about
Research objective: To explore the clinical application effect of multi-omics detection based on flow cytometry analysis, single-cell data and images combined with clinical features in differentiating the benign and malignant nature of pulmonary nodules and the early diagnosis of lung cancer
Who can take part
Age range
No age limits stated
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Patient underwent a ct examination
- Patient was confirmed to have pulmonary nodules
- Patient has been determined to undergo surgical treatment
- There are clear pathological results
- The clinicopathological data are complete
Exclusion criteria
- Patient has no ct examination results
- Refuse surgical treatment
- Patient has no clear pathological diagnosis
- Patients with hematogenic infectious diseases, such as HIV, hepatitis B or hepatitis C.
- Patients with tumor emergencies that require immediate treatment.
- Poor vascular conditions.
- Abnormal coagulation function or receiving anticoagulant or thrombolytic therapy.
- Patients with hematogenic infectious diseases, such as HBV.
- Patients with psychiatric disorders or severe mental illnesses.
- Patients who have difficulty communicating or are unable to be followed up for a long time
Where it is running
1 location listed.
- Soochow university - Suzhou, Jiangsu, China