Effect of Vitamin D on Cardiovascular Metabolic Risk in Overweight/Obesity Adolescents in China
Recruiting · NCT07053657 · Interventional (participants receive a specific treatment) · Lead sponsor: Anhui Medical University
View the official record on ClinicalTrials.gov →Interventions studied
Dietary Supplement: Vitamin D3Dietary Supplement: Vitamin D3 placebo
What this trial is about
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on cardiometabolic risk in Chinese adolescents with overweight/obesity and vitamin D deficiency. The main question it aims to answer whether vitamin D3 supplementation can improve cardiovascular metabolic health. Participants in the intervention group will receive vitamin D3. The control group will receive vitamin D placebo. Researchers will compare the change in cardiometabolic risk from baseline to post-intervention at 12 weeks between the intervention and control groups.
Who can take part
Age range
10 Years to 16 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Students whose caregivers signed informed consents;
- Students with serum 25(OH)D concentration of 12-20 ng/mL;
- Students with overweight or obesity.
Exclusion criteria
- Students with any disease that affects vitamin D metabolism (e.g., functional/organic brain disease, severe infectious disease, chronic gastrointestinal disease, hepatic or renal insufficiency, etc.);
- Students with known chronic disease (e.g., cardiovascular disease); use of vitamin D supplements in the past 3 months;
- Students with allergies to vitamin D or soybean oil ingredients.
Where it is running
2 locations listed.
- Anhui Medical University - Anqing, Anhui, China
- Anhui Medical University - Hefei, Anhui, China