The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Recruiting · NCT07060079 · Observational (researchers observe without assigning treatment) · Lead sponsor: University College, London
View the official record on ClinicalTrials.gov →What this trial is about
Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis. The investigation specifically focuses on sleep-disordered breathing (SDB) in individuals with chronic respiratory disease. SDB encompasses a range of conditions, the most common of which is obstructive sleep apnoea. In obstructive sleep apnoea, periodic pauses in breathing (apnoea) lead to reduced blood oxygen levels. To detect these events, patients typically undergo sleep studies that involve monitoring oxygen saturation, heart rate, and respiratory patterns during sleep. When chronic respiratory disease and SDB coexist, breathing disturbances during sleep may be exacerbated. To identify SDB, sleep studies are commonly used to assess oxygen levels, heart rate, and breathing patterns. The objective of this research is to identify differences between patients with chronic respiratory diseases who have SDB and those who do not. This will be achieved by analysing sleep study data using a novel analytical approach. The aim is to determine whether this method can yield more detailed insights into the underlying pathophysiology of these conditions.
Who can take part
Inclusion criteria
- All adult patients (≥ 18years) with chronic respiratory disease with/without SDB.
- patients who have had previously negative studies as a control group.
- Subject is able to read, understand, and sign the informed consent form.
- Willing to sleep with portable monitoring devices.
Exclusion criteria
- Patients who are under 18 years of age at the time of the index study.
- Contraindications to the use of portable monitoring.
- Inability to give informed consent to take part in the study.
Where it is running
1 location listed.
- Royal Free hospital - London, United Kingdom