Effect of Rehabilitation at Moderate Altitude on Airway Resistance Measured With Forced Oscillation Technique in COPD-patients
Recruiting · NCT07063563 · Interventional (participants receive a specific treatment) · Lead sponsor: Eastern Switzerland University of Applied Sciences
View the official record on ClinicalTrials.gov →Interventions studied
Oxygenambiant air
What this trial is about
Airway resistance will be measured using the forced oscillation technique (FOT). The parameters Rrs, Xrs, and ∆Xrs will be compared before and after a pulmonary rehabilitation cycle at moderate altitude. Additionally, the differences between low and moderate altitude will also be examined.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Aged ≥18 years
- Stable clinical condition for \>3 weeks (e.g., no exacerbations)
- Resting SpO₂ ≥88% and exercise-induced hypoxemia defined as a drop in SpO₂ of ≥4% and/or a level below 90% during the 6MWT
- Informed consent documented by signature
Exclusion criteria
- Severe daytime resting hypoxemia (SpO₂ \<88%)
- Long-term oxygen therapy
- Unstable clinical condition requiring adjustment of pharmacological or other treatment modalities, need for intensive care, or presence of relevant severe comorbidities
- Inability to comply with study procedures (e.g., due to language barriers, psychological disorders, neurological or orthopedic impairments, walking disability, or inability to ride a bicycle)
- Women who are pregnant or breastfeeding
- Enrolment in another clinical trial involving active treatment
Where it is running
2 locations listed.
- Eastern Switzerland University of Applied Sciences - Sankt Gallen, Canton of St. Gallen, Switzerland
- National center for cardiology and internal medicine - Bishkek, Kyrgyzstan, Kyrgyzstan