Memory Deterioration in Alzheimer Disease
Recruiting · NCT07118137 · Observational (researchers observe without assigning treatment) · Lead sponsor: Norwegian University of Science and Technology
View the official record on ClinicalTrials.gov →Interventions studied
7T MRIBlood samplesEEGNeuropsychologic test (MoCA)Stool samples
What this trial is about
Semantic AD
Who can take part
Age range
55 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Confirmed diagnosis based on current ICD criteria for AD or MCI .
- \>55years.
- Norwegian native speaker
- Lives at home and not in a health institution
Exclusion criteria
- Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR \> 2).
- Presence of brain tumors.
- History of traumatic brain injury.
- History of cranial surgery.
- Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).
- Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS.
- T MRI contraindications:
- Large tattoos close to the head region, permanent makeup or unremoveable piercings
- Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)
- Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)
Where it is running
1 location listed.
- Norwegian University of Sciene and Technology / Norges teknisk-naturvitenskapelige universitet (NTNU) - Trondheim, Trønderlag, Norway