A Brief Psychological Intervention to Improve Emotional Well-Being During Neoadjuvant Therapy for Pancreatic Cancer
Recruiting · NCT07124611 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
This clinical trial tests how well a psychosocial oncology intervention during neoadjuvant therapy works for patients with pancreatic cancer that has not spread to other parts of the body (localized). Chemotherapy and/or radiation therapy is often recommended prior to surgeryf or patients with pancreatic cancer; this is known as neoadjuvant therapy (NT). The primary advantages of NT include: reducing the size of the cancer mass and/or reducing the spread of cancer, to improve the likelihood of getting all the cancer during surgery, and because receiving chemotherapy after pancreas surgery can be challenging. Other research has shown that NT can lead to improved survival and a lower rate of the cancer returning. Despite these positive effects, NT can be associated with significant physical and emotional side effects. To prepare patients for future surgery and maintain health during chemotherapy and/or radiation, prehabilitation is often recommended. This can include nutritional and physical therapy to help with physical health. An oncology (cancer) psychosocial intervention during NT may be feasible and helpful to patients with localized pancreatic cancer.
Who can take part
Inclusion criteria
- Adults ≥ 18 years of age
- Patient:
- Newly diagnosed patients with localized pancreatic ductal adenocarcinoma (PDAC) presenting to Ohio State University Wexner Medical Center-Comprehensive Cancer Center (OSUMC-CCC)
- Plans to initiate neoadjuvant therapy prior to surgical resection
- Neoadjuvant therapy (NT) and/or surgery may occur at another facility
Exclusion criteria
- Prisoners
- Persons unable to provide consent
- Patients unlikely to undergo surgical resection following NT based on anatomical or performance status considerations
- Confirmed or presumed metastatic disease
- Already received ≥ 2 cycles of chemotherapy
Where it is running
1 location listed across 1 US state.
- Ohio State University Comprehensive Cancer Center - Columbus, Ohio, United States