Anastomotic Leakage After Colorectal Surgery.
Recruiting · NCT07144683 · Observational (researchers observe without assigning treatment) · Lead sponsor: Minia University
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Anastomotic leakage (AL) is a severe complication after colorectal surgery, with incidence rates of 2-30%. This prospective, single-center observational cohort study aims to identify and quantify independent risk factors for AL, determine its incidence and impact on outcomes, and develop a predictive model. Approximately 430 patients undergoing colorectal resection with anastomosis will be enrolled from August 2025 to August 2026. Risk factors will be assessed preoperatively, intraoperatively, and postoperatively. AL will be defined and graded per the International Study Group of Rectal Cancer (ISGRC) criteria.
Who can take part
Inclusion criteria
- Aged ≥18 years
- Undergoing elective or emergency colorectal resection with primary anastomosis (e.g., ileocolic, colocolic, colorectal, coloanal)
- Providing written informed consent
Exclusion criteria
- Colorectal resection without anastomosis (e.g., end stoma)
- Inflammatory bowel disease (Crohn's, ulcerative colitis)
- History of previous colorectal surgery involving anastomosis
- Pregnancy
- Unable to provide informed consent or comply with follow-up
Where it is running
1 location listed.
- Minia University Hospital - Minya, Minya Governorate, Egypt