No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study
Recruiting · NCT07146698 · Observational (researchers observe without assigning treatment) · Lead sponsor: Benha University
View the official record on ClinicalTrials.gov →Interventions studied
daily Interruption of Sedation
What this trial is about
this study is to compare no-sedation versus daily interruption of sedation (DIS) in Chronic obstructive pulmonary disease (COPD) patients receiving mechanical ventilation upon the ventilator-free days.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Patients of both sex aged 18 years or older
- The study will include 60 patients divided into 2 equal groups
- Invasive mechanical ventilation
- Patients with COPD patients (post-bronchodilator FEV1/FVC\< 70, and under follow through the department outpatient clinic) exacerbation admitted to the ICU and required invasive mechanical ventilation were recruited.
Exclusion criteria
- Allergy to sedative which will be used
- renal or hepatic impairment
- proven or suspected psychiatric or neurological impairment
- pregnancy
Where it is running
1 location listed.
- Benha University Hospitals - Banhā, Qalyubia Governorate, Egypt