HIV Prevention With PrEP Among People on Opioid Replacement Therapy
Recruiting · NCT07160075 · Interventional (participants receive a specific treatment) · Lead sponsor: Cara Spence
View the official record on ClinicalTrials.gov →Interventions studied
Simultaneous administration of OAT and oral PrEP at existing pharmacy-based programs
What this trial is about
The purpose of this study is to assess the feasibility and acceptability of providing oral pre-exposure prophylaxis (PrEP) and opioid agonist therapy (OAT) simultaneously in existing pharmacy-based programs operating in Alberta and Saskatchewan, to collect preference, adherence, and persistence data on oral PrEP, and to assess interest / acceptability of long-lasting injectable options for human immunodeficiency virus (HIV) prevention.
Who can take part
Age range
16 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- HIV negative
- Ongoing behaviors with potential HIV exposure as assessed by a clinician
- Regularly engaged with their respective OAT program at least 3 days a week for the past 2 weeks
- Report willingness to return for follow-up visits
Exclusion criteria
- Creatine clearance \<30 mL/min or any medical condition or medication known to be contraindicated with the use of Emtricitabine/Tenofovir Alafenamide (F/TAF) or Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF)
- Taken PrEP within the last 24 hours at the time of screening or enrollment
- Deemed appropriate by a clinician for HIV Post-Exposure Prophylaxis at the time of screening or enrollment
Where it is running
6 locations listed.
- Sheldon M Chumir Health Centre - Calgary, Alberta, Canada
- Queen City Wellness Pharmacy - Regina, Saskatchewan, Canada
- Mayfair Drugs Pharmacy - Saskatoon, Saskatchewan, Canada
- Pharmasave Riversdale Pharmacy - Saskatoon, Saskatchewan, Canada
- The Medicine Shoppe Pharmacy - Saskatoon, Saskatchewan, Canada
- Meadowgreen Pharmacy - Saskatoon, Saskatchewan, Canada