Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD
Recruiting · NCT07169123 · Observational (researchers observe without assigning treatment) · Lead sponsor: McMaster University
View the official record on ClinicalTrials.gov →What this trial is about
The study looks at how eating salt affects gut health in people with Crohn's disease. The aim of the study is to find out whether eating more salt increases the breakdown of proteins in the gut and if this makes inflammation and symptoms worse. By studying the link between salt, gut bacteria and inflammation, the study hopes to improve diet advice for people with Crohn's disease. This research may help find specific foods that affect the disease and lead to better, more personalized nutrition plans.
Who can take part
Age range
18 Years to 70 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- 18 and 70 years of age
- Crohn's disease diagnosis
- Willing and able to sign written informed consent prior to study entry
- Able to comply with the study procedures, in the opinion of the investigator
Exclusion criteria
- Antibiotics, antibacterial agents, or probiotics, currently, or within the last 8 weeks
- Alcohol or drug abuse
- Pregnancy
- Concurrent systemic disease and/or laboratory abnormalities considered by investigators to be a risk or that could interfere with data collection
Where it is running
2 locations listed.
- McMaster University - Hamilton, Ontario, Canada
- McMaster University Medical Centre - Hamilton, Ontario, Canada