AI-Guided Left Bundle Branch Area Pacing
Recruiting · NCT07206602 · Interventional (participants receive a specific treatment) · Lead sponsor: Mayo Clinic
View the official record on ClinicalTrials.gov →Interventions studied
AI-assisted Left Bundle Branch Area PacingLeft Bundle Branch Area Pacing
What this trial is about
The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age: 18 years or older.
- Left Ventricular Ejection Fraction (LVEF): \<50% within 6 months prior to enrollment.
- QRS Duration: Resting QRS duration ≥ 130 ms on ECG OR anticipated right ventricular pacing \> 40% OR device in place with right ventricular pacing \> 40% within 6 months prior to enrollment.
- Medical Therapy: Optimized on guideline-directed medical therapy for heart failure.
- AI-ECG probability of low LVEF: \>0.5
Exclusion criteria
- Age less than 18 years old
- Inability to follow-up
- Pregnancy
Where it is running
1 location listed across 1 US state.
- Mayo Clinic in Rochester - Rochester, Minnesota, United States