InRAD Observational Study
Recruiting · NCT07213700 · Observational (researchers observe without assigning treatment) · Lead sponsor: Stichting International Registry for Alzheimer's Disease and other Dementias Foundation
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this international observational study is to evaluate long-term disease outcomes and treatment safety in people with Alzheimer's disease (PwAD), by collecting real-world data from routine clinical practice across global clinical centers. The InRAD Registry Observational Study has several aims: * To collect medical information for many years from a large group of people with Alzheimer's disease. This will be used for research, which will support improved understanding about the disease. * To enable researchers to look at the effectiveness, usefulness and safety of treatments for Alzheimer's disease. * To enable researchers to answer similar research questions and compare results in many different areas of the world. People with Alzheimer's disease who meet the eligibility criteria and agree to participate in the Study will be asked to visit their doctor (e.g. psychiatrist, geriatrician, or neurologist) at least once a year, or as frequently as is needed for their care. During or after their appointments they may be offered assessments, tests, medications, and treatments as determined by their doctor and their team. This is an observational data collection.
Who can take part
Inclusion criteria
- Be undergoing diagnostic work-up for Alzheimer's disease (AD), OR
- Have a confirmed diagnosis of AD (whether currently treated with an AD-specific treatment, or untreated),
- Be attending an InRAD Center,
- Have provided informed consent for long-term follow-up
Exclusion criteria
- Any patient or legal representative who is unable or unwilling to provide a signed informed consent form
Where it is running
18 locations listed.
- Stichting Amsterdam UMC (location VUmc) - ABOARD Cohort - Amsterdam, Netherlands
- Stichting Amsterdam UMC (location VUmc) - Amsterdam Dementia Cohort - Amsterdam, Netherlands
- Aiginition Hospital - Athens, Greece
- Fundació ACE, Institut Català de Neurociències Aplicades - Barcelona, Spain
- County Emergency Clinic Hospital Brasov/Spitalul Clinic Judetean de Urgenta Brasov - Brasov, Romania
- The Adelaide and Meath Hospital - Dublin, Ireland
- B.R.A.N.D. Center - Neurologia Universitaria - Policinico Foggia - Foggia, Italy
- Medical University of Graz - Graz, Austria
- Istanbul University Çapa Hospital - Istanbul, Turkey (Türkiye)
- UZLeuven - Leuven, Belgium
- Alfred Hospital - Melbourne, Australia
- Ospedale San Raffaele - Milan, Italy
- Hospital de Santo António - Porto, Portugal
- Motol and Homolka University Hospital (UHM) - Prague, Czechia
- King Faisal Specialist Hospital - Riyadh, Saudi Arabia
- Kardinal Schwarzenberg Klinikum - Schwarzach, Austria
- Irmandade da Santa Casa de São Paulo - São Paulo, Brazil
- Panhellenic Federation of Alzheimer's Disease and Related Disorders - Thessaloniki, Greece