Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer
Recruiting · NCT07218601 · Interventional (participants receive a specific treatment) · Lead sponsor: Memorial Sloan Kettering Cancer Center
View the official record on ClinicalTrials.gov →Interventions studied
Breath sample collectionResearch blood collection
What this trial is about
The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure changes in certain chemicals in the breath before and after standard neoadjuvant therapy in people with NSCLC.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age ≥18
- Untreated clinical stage I NSCLC amenable to upfront surgery
- Untreated stage II to IIIB NSCLC amenable to neoadjuvant treatment followed by surgery
- ECOG Performance Status of ≤2 Of note, the E-nose is a completely noninvasive technology (only breath samples are collected). Therefore, this intervention would have no effects on a developing human fetus. There are therefore no requirements for the study population related to contraception or pregnancy testing.
Where it is running
7 locations listed across 2 US states.
- Memorial Sloan Kettering Basking Ridge (All Protocol Activities) - Basking Ridge, New Jersey, United States
- Memorial Sloan Kettering Monmouth (All Protocol Activities) - Middletown, New Jersey, United States
- Memorial Sloan Kettering Bergen (All Protocol Activities) - Montvale, New Jersey, United States
- Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities) - Commack, New York, United States
- Memorial Sloan Kettering Westchester (All Protocol Activities) - Harrison, New York, United States
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York, New York, United States
- Memorial Sloan Kettering Nassau (All Protocol Activities) - Uniondale, New York, United States