Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA
Recruiting · NCT07224789 · Observational (researchers observe without assigning treatment) · Lead sponsor: City of Hope Medical Center
View the official record on ClinicalTrials.gov →Interventions studied
cf-circRNA assay
What this trial is about
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Adults (≥18 years old)
- Histologically confirmed colorectal cancer (Stage I-III)
- Availability of pre-treatment plasma samples
- Written informed consent provided
Exclusion criteria
- History of other active malignancies within the past 5 years
- Poor sample quality or hemolysis
- Inability to provide informed consent
Where it is running
1 location listed across 1 US state.
- City of Hope Medical Center - Duarte, California, United States