TIVA Versus Balanced Anesthesia on Muscle Mass in CRC Surgery
Recruiting · NCT07237438 · Interventional (participants receive a specific treatment) · Lead sponsor: Grigore T. Popa University of Medicine and Pharmacy
View the official record on ClinicalTrials.gov →Interventions studied
sevoflurane anaesthesiatotal intravenous anaesthesia
What this trial is about
This study is aimed at clarifying changes in body composition during the perioperative period and identifying risk factors for skeletal muscle mass loss in patients with colorectal cancer. The investigators will asess the impact of the type of anaesthesia (total intravenous anaesthesia/sevoflurane anaesthesia) for colorectal surgery on the muscle function and mass, which will be evaluated using ultrasound, dynamometry and bioimpedance.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- adult patients diagnosed with colorectal cancer and scheduled for open colorectal surgery at the Regional Institute of Oncology, Iaşi, Romania
Exclusion criteria
- lack the capacity to consent
- extremity amputation
- paraplegia
- diseases affecting the muscles (such as stroke, lower-limb immobilization from a plaster, neurodegenerative diseases, peripheral neuropathy or muscle dystrophy)
- terminal cancer
Where it is running
1 location listed.
- Regional Institute of Oncology, Iaşi, Romania - Iași, Romania