Antrodia Cinnamomea Extract Effects on Lung Cancer Patients' Quality of Life During Chemotherapy
Recruiting · NCT07241182 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
Antrodia cinnamomea supplementTurmeric-Probiotic Group
What this trial is about
This randomized trial will test whether Antrodia cinnamomea supplement improves quality of life in lung cancer patients receiving platinum-based chemotherapy. Participants at Tri-Service General Hospital will be randomized to receive either Antrodia cinnamomea capsules or placebo for 3 months, with follow-up to 6 months (24 weeks). Primary outcomes include nausea/vomiting scores, sleep quality, quality of life, and cancer symptoms.
Who can take part
Age range
18 Years to 99 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Pathologically and radio-graphically diagnosed lung cancer
- Age greater than 18 years
- Received platinum-based chemotherapy
- Life expectancy of six months or longer
Exclusion criteria
- Inability to comply with timely supplementation administration.
- Within 14 days prior to trial entry, laboratory data showing abnormal liver function, abnormal kidney function
- Within 30 days prior to trial entry, unexplained fever ≥38.5°C for 7 consecutive days or chronic diarrhea for 15 consecutive days.
- Currently receiving hormone therapy.
- Major cardiac disease or arrhythmia severe enough that the attending physician considers the patient unsuitable for trial participation.
- Major neuropathy.
- Patients with currently active acute infections.
- Patients with known allergies/allergic reactions to the investigational product or any components in their formulations.
- Patients currently taking supplements containing Antrodia camphorata extract.
Where it is running
1 location listed.
- Tri-Service General Hospital - Taipei, Taiwan