A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Recruiting · NCT07241390 · Interventional (participants receive a specific treatment) · Lead sponsor: Eli Lilly and Company
View the official record on ClinicalTrials.gov →Interventions studied
OrforglipronPlacebo
What this trial is about
The purpose of this study is to measure cardiovascular outcomes with orforglipron compared with placebo in participants with atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD). Participation in the study will last about 5 years.
Who can take part
Age range
50 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 3
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Have established ASCVD and/or CKD
Exclusion criteria
- Have type 1 diabetes
- Have had a major heart condition within 60 days prior to screening
- Have New York Heart Association Functional Classification Class IV heart failure
Where it is running
60 locations listed.
- Jeroen Bosch Hospital - 's-Hertogenbosch, Netherlands
- Centro de Atencion al Diabetico Actopan - Actopan, Mexico
- Adana Sehir Egitim ve Arastirma Hastanesi - Adana, Turkey (Türkiye)
- Nightingale Research - Adelaide, Australia
- Afyon Kocatepe Üniversitesi Tıp Fakültesi - Afyonkarahisar, Turkey (Türkiye)
- Gujarat Endocrin Pvt Ltd - Ahmedabad, India
- EB Medical Research - Almere Stad, Netherlands
- Centro Periférico de Especialidades Bola Azul - Almería, Spain
- Klinikiniai Sprendimai, JSC - Alytus, Lithuania
- Hospital Universitario de La Ribera - Alzira, Spain
- Meander Medisch Centrum - Amersfoort, Netherlands
- OLVG Oost - Amsterdam, Netherlands
- Amsterdam UMC, locatie AMC - Amsterdam, Netherlands
- Ankara Etlik City Hospital - Ankara, Turkey (Türkiye)
- Akdeniz Universitesi Hastanesi - Antalya, Turkey (Türkiye)
- Gelre Ziekenhuis - Apeldoorn, Netherlands
- Centro de Pesquisa Clinica do Coracao - Aracaju, Brazil
- Fundacion Cardiomet Cequin - Armenia, Colombia
- Ziekenhuis Rijnstate - Arnhem, Netherlands
- Assuta Ashdod Medical Center - Ashdod, Israel
- Barzilai Medical Center - Ashkelon, Israel
- Athens Medical Center - Psychikon branch - Athens, Greece
- Alexandra General Hospital of Athens - Athens, Greece
- Athens Medical Center - Athens, Greece
- Aotearoa Clinical Trials - Auckland, New Zealand
- Hospital Universitario de Badajoz - Badajoz, Spain
- Hospital Germans Trias i Pujol - Badalona, Spain
- Baguio General Hospital - Baguio City, Philippines
- Instituto de Investigaciones Clínicas Bahia Blanca - Bahía Blanca, Argentina
- CMI Cardiologie - Dr. Mercea Corina Delia - Baia Mare, Romania
- CMI DNBM Dr. Pop Lavinia - Baia Mare, Romania
- DRC Gyógyszervizsgáló Központ - Balatonfüred, Hungary
- Spitalul Clinic De Urgenta Prof Dr Agrippa Ionescu - Baloteşti, Romania
- Life Care Hospital and Research Centre - Bangalore, India
- Faculty of Medicine Siriraj Hospital - Bangkok, Thailand
- Hospital Universitari Vall d'Hebron - Barcelona, Spain
- Clinica de la Costa S.A.S. - Barranquilla, Colombia
- Corazon IPS - Barranquilla, Colombia
- IPS Centro Científico Asistencial S.A.S - Barranquilla, Colombia
- Soroka Medical Center - Beersheba, Israel
- Peking University People's Hospital - Beijing, China
- Peking University Third Hospital - Beijing, China
- Beijing Pinggu District Hospital - Beijing, China
- KLES Dr. Prabhakar Kore Hospital & M.R.C - Belagavi, India
- Belagavi Institute of Medical Sciences - Belagavi - Belagavi, India
- Clinical Center of Serbia - Belgrade, Serbia
- NUPEC - Cardio - Belo Horizonte, Brazil
- University Center of Belo Horizonte - Campus Buritis - Belo Horizonte, Brazil
- Hospital Universitário João de Barros Barreto - Belém, Brazil
- All India Institute of Medical Sciences - Bhubaneswar, India
- Uniwersytecki Szpital Kliniczny w Białymstoku - Bialystok, Poland
- Zdrowie Osteo-Medic - Bialystok, Poland
- Specderm Poznanska sp.j. - Bialystok, Poland
- FutureMeds - Birmingham - Birmingham, United Kingdom
- Layton Medical Centre - Blackpool, United Kingdom
- Paratus Clinical Research Western Sydney - Blacktown, Australia
- AngioKormann Blumenau - Blumenau, Brazil
- Hospital Universitario HM Monteprincipe - Boadilla del Monte, Spain
- Hospital Universitario Mayor Méderi - Bogotá, Colombia
- Bluecare Salud S.A.S - Bogotá D.C., Colombia
Showing 60 of 566 listed sites. See the official record for the complete list.
Read the full protocol, contacts and eligibility on ClinicalTrials.gov →