Supplementation With Sirtuin Activators in Women With Increased Body Weight
Recruiting · NCT07245979 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are: Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing? Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status. Participants will: Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.
Who can take part
Inclusion criteria
- females
- age: 40-65 years
- overweight or obese: BMI \>25 kg/m2
Exclusion criteria
- males
- BMI \< 25 kg/m2
- sirtuin activators administration for 3 months prior to study
- pregnancy or breastfeeding
- recent dieting or being on calorie restricted diet
- receiving pharmacotherapy to treat obesity, diabetes or hyperlipidemia
- post-bariatric surgery
- diabetes
- cancer
- chronic kidney, liver or autoimmune diseases
- alcohol addiction
Where it is running
1 location listed.
- Poznan University of Life Sciences - Poznan, Poland