Stress and Anxiety Effects on Valuation
Recruiting · NCT07252947 · Interventional (participants receive a specific treatment) · Lead sponsor: NYU Langone Health
View the official record on ClinicalTrials.gov →Interventions studied
Non-Stressful Control TaskSocially Evaluated Cold Pressor Task (SECPT)
What this trial is about
The purpose of this study is to understand how stress, anxiety, and negative affect change learning and decision-making processes. The primary objective is to assess two forms of decision-making-reward adaptation and emotion prediction errors-differ as a function of stress and anxiety. The secondary objectives are to assess how individual differences measured in our studies relate to these decision variables.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Aims 1-3: To be eligible for participation in this study, an individual must meet all of the following criteria:
- 18-65 years of age
- Able to speak, read, and write fluently in English
- Be willing and able to follow study procedures and provide informed consent.
- Aim 4: To be eligible for participation in this study, an individual must meet all of the following criteria:
- 18-65 years of age
- Diagnosis of GAD
- Able to speak, read, and write fluently in English
- Be willing and able to follow study procedures and provide informed consent.
Exclusion criteria
- Aims 1-3: Individuals will be excluded from participation if any of the following criteria are met:
- History of or medication for neurologic or psychiatric disease
- High-blood pressure or heart condition
- Diabetes, food allergies, metabolic disorders or history of eating disorder
- Use of corticosteroids or beta-blockers
- Pregnancy
- Aim 4: Individuals will be excluded from participation if any of the following criteria are met:
- High-blood pressure or heart condition
- Diabetes, food allergies, metabolic disorders or history of eating disorder
- Use of corticosteroids or beta-blockers
- Lifetime history of bipolar disorder or any psychotic disorder; substance use disorder in past 3 months; eating disorder in past 6 months; current major depressive disorder (past is allowed)
- Active suicidal ideation with plan and intent (indicated by score \>=4 on the Columbia Suicide Severity Scale)
- Not on stable dose of psychiatric medication for at least 4 weeks prior to study participation
- Pregnancy
Where it is running
1 location listed across 1 US state.
- NYU Langone Health - New York, New York, United States