Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus
Recruiting · NCT07281040 · Observational (researchers observe without assigning treatment) · Lead sponsor: Hull University Teaching Hospitals NHS Trust
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Aims and Objectives 1. Choose which adjunctive therapies, at what dose, and for how long 2. Choose the dose(s) of IV furosemide to be used as the comparator 3. Choose primary and secondary outcomes 4. Estimate recruitment and engage sites for a future trial Work package 2a methods overview 1. An online survey of clinicians (doctors, nurses and pharmacists) assessing potential ability to recruit and the acceptability of each adjunct and willingness to support a trial. 2. Evidence generated (survey and reviews) will be considered by an expert panel (N=20-25) including expert clinicians and allied health professionals who care for people with HF using a modified Delphi approach. The panel will make recommendations on all aspects of the trial design. 3. A patient and carer panel of people with a recent hospitalisation (\<6 months) for HF will provide recommendations on trial endpoints. The patient-and-carer advisory group (PCAG) will also input into these discussions.
Who can take part
Inclusion criteria
- Recent hospitalisation with heart failure (\<6 months) or carer for a person with a recent hospitalisation with heart failure.
- Able to participate in online group discussions in English
Exclusion criteria
- \. Unable to participate in online group discussions in English
Where it is running
1 location listed.
- Cardiology - Hull, Yorkshire, United Kingdom