Predicting the Pain Outcome of Surgery for Endometriosis
Recruiting · NCT07313345 · Observational (researchers observe without assigning treatment) · Lead sponsor: University of Oxford
View the official record on ClinicalTrials.gov →Interventions studied
Surgical treatment of endometriosis
What this trial is about
This study aims to determine whether the investigators can predict who will get benefit in terms of their pain from surgery for more severe forms of endometriosis. The investigators will use brain imaging to explore this, as it allows meaningful results from a smaller sample of people than if questionnaires alone were relied on.
Who can take part
Age range
18 Years to 50 Years
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- willing and able to give informed consent
- aged between 18 and 50 years of age
- female or born female
- diagnosed with stage III or IV endometriosis by scan (MRI or USS) or previous surgery
- surgical treatment of severe endometriosis planned (surgical procedure at discretion of operating surgeon)
- reports pelvic pain of ≥4/10 (measured using a 0 - 10 numerical rating scale asking about the participant's worst pelvic pain associated with their endometriosis)
- reasonably fluent in English
- in the Investigator's opinion, is able and willing to comply with all study requirements
- willing to allow his or her General Practitioner and consultant to be notified of participation in the study
Exclusion criteria
- pregnant, lactating or planning pregnancy during the course of the study
- contraindication to MRI
Where it is running
1 location listed.
- Oxford University Hospitals Foundation Trust - Oxford, Oxfordshire, United Kingdom