The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study
Recruiting · NCT07315997 · Observational (researchers observe without assigning treatment) · Lead sponsor: Brigham and Women's Hospital
View the official record on ClinicalTrials.gov →Interventions studied
high sensitivity cardiac troponin
What this trial is about
Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.
Who can take part
Age range
35 Years to 79 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- RA diagnosed by a rheumatologist
- Age 40- 79
- ≥1 ASCVD risk factor including prediabetes, hypertension, BMI \>30, current or history of cigarette smoking
Exclusion criteria
- Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor
- Patients with diabetes mellitus
- Pregnancy
Where it is running
3 locations listed across 1 US state.
- Massachusetts General Hospital: Rheumatology - Boston, Massachusetts, United States
- Brigham and Womens Hospital - Boston, Massachusetts, United States
- Brigham and Women's Faulkner Hospital - Boston, Massachusetts, United States