IMT in Asthma: Activity, Coping, Self-Management
Recruiting · NCT07320066 · Observational (researchers observe without assigning treatment) · Lead sponsor: Istanbul Esenyurt University
View the official record on ClinicalTrials.gov →Interventions studied
other
What this trial is about
The aim of this study is to investigate asthma patients' experiences with an 8 week IMT and the perceived effects of this intervention on physical activity, coping strategies, and asthma self-management. A qualitative methodological design will be applied to understand the experiences of patients participating in the IMT program, how the program affected their daily activities, how they coped with symptoms and difficulties, and how they managed their condition.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Being between the ages of 18-65
- Having been diagnosed with severe persistent, non-allergic asthma by a pulmonologist in accordance with the Global Initiative for Asthma (GINA) guideline criteria,
- Patients with type 2 inflammation markers. According to accepted standards; peripheral eosinophils \<150/µL and/or negative skin prick test and/or total IgE \<30 kU/L
- Bronchodilator response (\>12% or 200 mL improvement in FEV1% predicted following inhalation of 400 mg salbutamol)
- Diagnosis-follow-up period: Patients diagnosed at least 6 months prior, under follow-up and treatment, and/or with controlled asthma
- Having completed the pulmonary rehabilitation program
- Completion of 8 weeks of inspiratory muscle training (IMT)
- Patients who have read, understood, and signed the informed consent form
Exclusion criteria
- Having recently had a respiratory tract infection recently (within the last month),
- Having a smoking history of more than 10 pack-years or having a history of smoking within 6 months after quitting smoking
- Having received oral corticosteroid treatment in the last 4 weeks,
- Having a Body Mass Index \>35,
- Eosinophilic Granulomatosis Polyangiitis (EGPA) and Allergic Bronchopulmonary Aspergillosis (ABPA),
- Vasculitis,
- History of malignancy,
- Pregnancy,
- Previous lung surgery, use of long-term oxygen therapy
- Having accompanying restrictive lung diseases (advanced kyphoscoliosis, ankylosing spondylitis) and neuromuscular diseases (myastania gravis, muscular dystrophies, myopathies) that will prevent healthy respiratory function testing and rehabilitation.
- Cognitive dysfunction, mental retardation, dementia, or other conditions that make it difficult to follow the protocol,
- Unwillingness to continue participating in the study,
- Communication difficulties or intellectual deficiencies
Where it is running
1 location listed.
- Istanbul Esenyurt University - Istanbul, Istanbul, Turkey (Türkiye)