Correlation Between Vaspin Gene Polymorphism and Serum Vaspin Levels in Psoriasis Vulgaris
Recruiting · NCT07320872 · Observational (researchers observe without assigning treatment) · Lead sponsor: Aswan University
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Psoriasis is a common immune-mediated inflammatory skin disease affecting at least 100 million individuals worldwide. In Egypt, the prevalence of psoriasis ranges between 0.19% and 3% of the Egyptian people. It is associated with poor quality of life, reduced life expectancy and multimorbidity including psoriatic arthritis, obesity and cardiovascular disease. Vaspin (VASP, SERPIN 12) is a recently discovered adipokine that has been isolated from the visceral adipose tissue of a rat model of type 2 diabetes. It is coded by the gene SERPNA12 located on the long arm of chromosome 14q32.13 and consists of six exons and five introns.
Who can take part
Inclusion criteria
- Newly diagnosed cases or stopped treatment of at least 6 months of psoriasis patients.
- Pateints with any age and gender.
Exclusion criteria
- Pregnancy and lactation.
- Patients with chronic diseases: cardiac diseases, hepatic disorders, chronic renal failure or malignancies.
- Patients with associated inflammatory disease such as infections and autoimmune diseases.
Where it is running
1 location listed.
- Aswan University Hospital - Aswān, Egypt