Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)
Recruiting · NCT07327489 · Observational (researchers observe without assigning treatment) · Lead sponsor: Elephas
View the official record on ClinicalTrials.gov →Interventions studied
Biopsy
What this trial is about
This study will collect tumor specimens with correlated clinical and demographic data from patients who are undergoing a biopsy or similar procedure to obtain tumor tissue as a normal course of their medical management or diagnostic work-up for suspected or confirmed cancer.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Able and willing to provide informed consent for participation
- Age ≥18 years at time of consent.
- Have a suspected or confirmed cancer diagnosis that is to be evaluated by means of a biopsy.
- Subjects who are newly diagnosed or have suspected cancer must be treatment-naïve at the time of biopsy. All other subjects should have the biopsy performed before starting their next line of treatment.
Exclusion criteria
- Have a known auto-immune disease or prior condition (prior organ transplant, chronic kidney or liver disease) that renders them ineligible for immunotherapy (IO) treatment.
- Severely immunocompromised person(s). Examples include patients on immunosuppressants, HIV positive patients on antiretrovirals, post transplantation patients.
- Pregnant person(s).
Where it is running
16 locations listed across 5 US states.
- Mercy Hospital - FTS - Fort Smith, Arkansas, United States
- Mercy Hospital - FTS - Fort Smith, Arkansas, United States
- Frederick Health Hospital - Frederick, Maryland, United States
- Frederick Health Hospital - Frederick, Maryland, United States
- Mercy Hospital - SPG - Springfield, Missouri, United States
- Mercy Hospital - SPG - Springfield, Missouri, United States
- Mercy Hospital - South - St Louis, Missouri, United States
- Mercy Hospital -STL - St Louis, Missouri, United States
- Mercy Hospital - South - St Louis, Missouri, United States
- Mercy Hospital -STL - St Louis, Missouri, United States
- Mercy Hospital - OKC - Oklahoma City, Oklahoma, United States
- Mercy Hospital - OKC - Oklahoma City, Oklahoma, United States
- JPS Health Network - Forth Worth, Texas, United States
- JPS Health Network - Forth Worth, Texas, United States
- Baylor Scott and White Biorepository - Temple, Texas, United States
- Baylor Scott and White Biorepository - Temple, Texas, United States