To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital
Recruiting · NCT07337434 · Interventional (participants receive a specific treatment) · Lead sponsor: Syeda Sana Zaman
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
This study aims to compare efficacy of methotrexate vs apremilast in the management of chronic plaque psoriasis.Given the high prevalence of psoriasis in Pakistan and the significant psychological impact on patients, particularly in Peshawer,this study will provide valuable insights into optimal treatment strategies.
Who can take part
Age range
18 Years to 60 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Early Phase 1
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Patients having age between 18-60 years of either gender Diagnosed with moderate to severe plaque psoriasis (PASI ≥10) No prior systemic therapy in past 3 months.
Exclusion criteria
- Pregnancy or lactation History of liver or renal dysfunction Known hypersensitivity to study drugs
Where it is running
1 location listed.
- MTI-HMC Peshawar - Peshawar, Khyber Pukhtunkhwa, Pakistan