Electrophysiology-based DBS Programming for PD
Recruiting · NCT07348705 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Florida
View the official record on ClinicalTrials.gov →Interventions studied
Broad-band electrophysiology-based DBS programmingClinician-based DBS programmingMaximum Beta power-based DBS programming
What this trial is about
Deep brain stimulation (DBS) effectively alleviates motor symptoms in Parkinson's disease (PD). However, current programming is manual and time-consuming. This study will evaluate physiology-based programming using local field potentials (LFPs) to identify optimal stimulation parameters. Specifically, DBS contact selection based on beta power and a broad-band approach will be compared with conventional clinician-based programming.
Who can take part
Age range
21 Years to 89 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Patients with a diagnosis of idiopathic PD fulfilling the Movement Disorder Society Clinical Diagnostic Criteria for PD
- DBS implantation with the Percept DBS device (Medtronic, USA) for the treatment of motor symptoms
- Ability to give informed consent for the study
- Willingness to do this study at the time of the initial programming session
- Age 21 to 89 years old
Exclusion criteria
- Inability to comply with the study protocol
- Atypical Parkinsonism
- Any personality or mood symptoms that study personnel believe will interfere with the study requirements
Where it is running
1 location listed across 1 US state.
- Norman Fixel Institute for Neurological Diseases - Gainesville, Florida, United States