Pentoxifylline in Patients With Ulcerative Colitis
Recruiting · NCT07349472 · Interventional (participants receive a specific treatment) · Lead sponsor: Ihab Elsayed Hassan
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Ulcerative colitis (UC) is a persistent, idiopathic form of inflammatory bowel disease (IBD) marked by uninterrupted inflammation of the colon's mucosal lining, usually starting at the rectum and progressing proximally in a continuous manner. It manifests clinically with recurrent episodes of abdominal pain, bloody diarrhea, urgency, tenesmus, and weight loss. The precise cause of UC is still unknown; however, it is thought to arise from a multifactorial interaction involving genetic susceptibility, immune system dysregulation, disturbances in gut microbiota composition, and various environmental factors.
Who can take part
Inclusion criteria
- Age ≥ 18 years
- Both male and female will be included
- Negative pregnancy test and effective contraception.
- Mild and moderate UC patients
Exclusion criteria
- Breast feeding
- Significant liver and kidney function abnormalities
- Diabetic patients
- Colorectal cancer patients
- Patients with severe UC
- Patients taking rectal or systemic steroids
- Patients taking immunosuppressives or biological therapies
- Addiction to alcohol and / or drugs
- Known allergy to the studied medications
Where it is running
1 location listed.
- Fayoum University - Al Fayyum, Egypt