Zesty Exercise System for Therapeutic Engagement

Recruiting · NCT07382674 · Interventional (participants receive a specific treatment) · Lead sponsor: Emory University

View the official record on ClinicalTrials.gov →

Interventions studied

ZEST-E Robot-Assisted Exercise Program

What this trial is about

This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely. Participants will complete robot-guided exercise three times per week for three weeks. The study will assess feasibility, retention, safety, acceptability, and tolerability of remotely monitored ZEST-E and will measure changes in functional performance using the Standing Forward Reach test and the 30-Second Chair Stand test. These outcomes reflect range of motion and lower-body strength targeted by the exercise program.

Who can take part

Age range

40 Years and older

Sex

All (male and female)

Healthy volunteers

No - a diagnosis or condition is required

Phase

Not applicable (e.g. observational or device study)

Study type

Interventional (participants receive a specific treatment)

Inclusion criteria

lder adults with mild to moderate PD.

Exclusion criteria

Acute medical illness requiring hospitalization;
Under 40 years old;
Uncontrolled congestive heart failure;
History of stroke in the past three years;
Inability to perform study procedures;
Medical or physical conditions that would preclude participation (e.g., severe arthritis or mobility problems, uncontrolled hypertension or diabetes, renal failure, history of angina with activity);
On medications that could adversely affect cognition, e.g.: antipsychotics, opioids, stimulants, chemotherapy;
Psychotic disorders;
Confounding neurologic conditions (e.g., active central nervous system opportunistic infections, seizure disorders, head injury with loss of consciousness \>30 minutes, intracranial neoplasms, stroke with neurological or neuropsychiatric sequelae);
Substance Use Disorder, Major Depressive and Generalized Anxiety Disorders within six months of evaluation;
Hohn \& Yahr \> 3
MoCA \<17

Where it is running

1 location listed across 1 US state.

Emory University, 57 Executive Park S NE, Ste 200 - Atlanta, Georgia, United States

Read the full protocol, contacts and eligibility on ClinicalTrials.gov →