Cardiac Remodelling Following Endovascular Repair of the Aorta
Recruiting · NCT07415447 · Observational (researchers observe without assigning treatment) · Lead sponsor: Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
View the official record on ClinicalTrials.gov →Interventions studied
cardiac magnetic ressonance
What this trial is about
To assess the effects of endovascular aortic repair on cardiac morphology and function
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- \- Patients over 18-year-old, with degenerative arch, descending thoracic or abdominal aortic aneurysms, penetrating aortic ulcers or intramural hematomas managed with total EVAR in elective setting.
Exclusion criteria
- Heart failure with an ejection fraction \<35 vs 50% or New York Heart Association (NYHA) class III and IV.
- LV wall motion abnormality.
- Moderate to severe valve disease.
- History of (or expected within the study period) cardiac/aortic surgery.
- Coronary artery disease.
- Atrial fibrillation.
- Congenital heart disease.
- Connective tissue disorders.
- Chronic kidney disease (eGFR \<30 mL/min/173 m2).
- Moderate to severe pulmonary disease as indicate either by post bronchodilator FEV1 (%predicted) \<50% or Modified Medical Research Council Dyspnoea Scale (mMRC) 3-4.
- CMR contraindications (non-compatible pacemakers and metal implants, and claustrophobia).
Where it is running
2 locations listed.
- Unidade Local de Saúde Santa Maria - Lisbon, Portugal
- Unidade Local de Saúde de Santa Maria, E.P.E. - Lisbon, Portugal