Identify a Specific Immune Profile in Patients With Chronic Pelvic Pain Resistant to First-line Treatments by Measuring Th1, Th2, Th17, and Treg Cytokines Produced After Non-specific Functional Cell Stimulation - ImmunoCPP
Recruiting · NCT07429773 · Interventional (participants receive a specific treatment) · Lead sponsor: Centre Hospitalier Universitaire de Nice
View the official record on ClinicalTrials.gov →Interventions studied
Immune profile
What this trial is about
Chronic pelvic pain (CPP) affects more than one in four women. An immune imbalance in the Th1/Th2 balance has been reported in multiple CPP situations, particularly in patients with endometriosis, but with mixed results. The use of a functional immune test, already validated in previous indications and particularly in infertility, could simulate an immune stimulation similar to that of painful attacks.
Who can take part
Age range
18 Years to 40 Years
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Aged between 18 and 40;
- Under continuous hormone treatment for at least 6 months;
- Imaging less than 12 months old: either normal or showing endometriosis and/or adenomyosis lesions, excluding any other abnormalities that could explain the PCOS;
- Affiliation with the French Social Security system;
- Signature of informed consent.
Exclusion criteria
- Pregnant or breastfeeding women;
- Autoimmune disease;
- History of cancer within the last 5 years or currently undergoing treatment;
- Current infectious syndrome;
- Person under guardianship or conservatorship.
Where it is running
1 location listed.
- CHU Nice - Hôpital de l'Archet 2 - Nice, Alpes-Maritimes, France