Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)
Recruiting · NCT07435467 · Observational (researchers observe without assigning treatment) · Lead sponsor: Istituto Nazionale di Ricovero e Cura per Anziani
View the official record on ClinicalTrials.gov →Interventions studied
collection of blood samples
What this trial is about
The BAD-GER study is a multicenter, prospective, three-arm observational study serving to validate a prognostic biomarker algorithm for mortality and hospital readmission; this algorithm will be developed through the retrospective analysis of Alzheimer's Disease and neurodegeneration biomarkers in an already available discovery cohort of 700 previously hospitalized geriatric patients.
Who can take part
Age range
65 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis/meningitis
Exclusion criteria
- no informed consent
- GROUP 2: Patients hospitalized for non-neurological diseases with dementia
- Inclusion criteria:
- inpatients with diagnosis of major neurocognitive disorder according to DSM-5 criteria (2013)
- Exclusion criteria:
- Inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis/meningitis
- no informed consent
- GROUP 3: Patients hospitalized for non-neurological diseases without dementia
- Inclusion criteria:
- inpatients with non-neurological diseases
- Exclusion criteria:
- inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis/meningitis
- diagnosis of dementia
- no informed consent
Where it is running
3 locations listed.
- IRCCS INRCA Hospital - Ancona, Italy
- IRCCS INRCA Hospital - Fermo, Italy
- Policlinico Universitario - Messina, Italy