Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
Recruiting · NCT07446296 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Pennsylvania
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant. The study will also learn how acceptable and useful this program is for participants. The main questions it aims to answer are: * Can a remote exercise program be delivered successfully to people on the kidney transplant waiting list? * Do participants follow the exercise program and wear a physical activity tracker as asked? * Is the program safe and well tolerated? Researchers will compare two groups to see if the exercise program leads to higher physical activity and better physical function: * Usual pre-transplant care with a physical activity tracker * Usual pre-transplant care plus an online exercise program Participants will: * Wear a wrist activity tracker to measure daily physical activity * Complete a one-week baseline period before being assigned to a study group * Be randomly assigned (like flipping a coin) to one of two groups * If assigned to the exercise group, take part in online exercise classes at home for 12 weeks with reminders and feedback, and then another 12 weeks without reminders and feedback * Answer questionnaires about their health, activity, and experience in the study This study may help researchers learn how to better support people waiting for kidney transplant through safe, home-based exercise programs.
Who can take part
Inclusion criteria
- be at least 60 years old
- receive transplant care at Penn Medicine
- be on the kidney transplant waiting list
- speak and comprehend English
- be able to walk
- have at least one physical function limitation OR at least one frailty metric
- have access to a device capable of connecting to the Internet and downloading an application
- be able to provide written informed consent
- be cleared for participant via the Physical Activity Readiness Questionnaire (PARQ) verified against medical record or via written medical clearance from a clinician
Exclusion criteria
- Have had a myocardial infarction or a stroke in the 3 months immediately prior to enrollment
- Be unable to self-monitor with study devices (i.e., have a condition such as dementia)
- Not cleared by PARQ or receive written medical clearance to exercise
- Participate in another physical activity study
- Have any other reason they do not expect to be able to complete the study
Where it is running
1 location listed across 1 US state.
- Perelman Center for Advanced Medicine - Philadelphia, Pennsylvania, United States