Real-World Case Registry Study on Obesity
Recruiting · NCT07448090 · Observational (researchers observe without assigning treatment) · Lead sponsor: Hubei Hospital of Traditional Chinese Medicine
View the official record on ClinicalTrials.gov →What this trial is about
Obesity is a major risk factor for cardiovascular disease, diabetes, cancer, and other chronic conditions. Due to its complex etiology and frequent comorbidities, effective obesity management requires comprehensive and individualized approaches. This study is a multicenter, prospective, real-world registry designed to evaluate integrated traditional Chinese medicine (TCM) and Western medicine interventions for obesity. The study will enroll at least 10,000 individuals with obesity from urban and rural populations. Multimodal data, including electronic medical records, laboratory test results, imaging data, and lifestyle information, will be collected. The effectiveness of integrated TCM and Western medicine interventions will be assessed across different age groups, disease stages, and obesity-related constitution types. In addition, disease progression patterns and key prevention and treatment points will be explored. Health economic analyses will be conducted to evaluate the cost-effectiveness of different obesity management strategies, providing real-world evidence to support public health policy and the optimization of integrated obesity prevention and management approaches.
Who can take part
Inclusion criteria
- Age 18 years and above, gender not restricted;
- Weight fluctuation within the last 3 months is ≤ 5% and BMI is ≥ 28.0 kg/m2;
- Good compliance, willing to follow the follow-up principles;
- Agree to sign the informed consent form.
Exclusion criteria
- Co-existing severe diseases of the heart, liver, lungs, kidneys, brain, blood, neuro-psychiatric system, or other vital organs.
- Secondary obesity (obesity attributable to another clearly diagnosed disorder, e.g., hypothalamic or pituitary inflammation, tumours or trauma, Cushing's syndrome, hypothyroidism, hypogonadism, polycystic ovary syndrome, etc.).
- Iatrogenic obesity (obesity resulting from drugs or therapeutic interventions administered for other conditions).
- Pregnant or lactating women.
- Subjects whom the investigator deems unsuitable for participation in this study.
Where it is running
1 location listed.
- Hubei Provincial Hospital of Traditional Chinese Medicine - Wuhan, Hubei, China