Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases
Recruiting · NCT07449117 · Interventional (participants receive a specific treatment) · Lead sponsor: Masaryk University
View the official record on ClinicalTrials.gov →Interventions studied
Active Temporal Interference Stimulation (TIS)Placebo / Sham TIS
What this trial is about
The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.
Who can take part
Age range
60 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), in Parkinson's Disease (MCI-PD) or Amnestic Mild Cognitive Impairment (aMCI).
Exclusion criteria
- Any severe psychiatric disorder.
- History of other neurological diseases affecting the central nervous system.
- Severe head trauma.
- Uncompensated internal or oncological disease.
- Presence of MRI-incompatible metal in the body (e.g., pacemaker).
Where it is running
1 location listed.
- CEITEC MU (Central European Institute of Technology, Masaryk University) - Brno, South Moravian, Czechia